A Bayesian Binomial Regression Model with Latent Gaussian Processes for Modelling DNA Methylation
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Austrian Statistical Society
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Abstract
Epigenetic observations are represented by the total number of reads from a given pool of cells and the number of methylated reads, making it reasonable to model this data by a binomial distribution. There are numerous factors that can influence the probability of success in a particular region. Moreover, there...
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Genomics (q-bio.GN) , FOS: Computer and information sciences , 330 , Statistics , Statistics - Applications , Quantitative Biology - Quantitative Methods , QA273-280 , 510 , HA1-4737 , Methodology (stat.ME) , FOS: Biological sciences , Quantitative Biology - Genomics , Applications (stat.AP) , Probabilities. Mathematical statistics , Statistics - Methodology , Quantitative Methods (q-bio.QM)