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Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

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dc.contributor.author Sanna Toppila-Salmi
dc.contributor.author Sophie Scheire
dc.contributor.author Thibaut Van Zele
dc.contributor.author Job F M van Boven
dc.contributor.author Mika J. Mäkelä
dc.contributor.author Laura Pujols
dc.contributor.author Peter Hellings
dc.contributor.author Koen Boussery
dc.contributor.author Isam Alobid
dc.contributor.author Ralph Mösges
dc.contributor.author Philippe Gevaert
dc.contributor.author Martin Wagemann
dc.contributor.author Carmen Rondon
dc.contributor.author P. V. Tomazic
dc.contributor.author Claire Hopkins
dc.contributor.author Ioana Agache
dc.contributor.author Wytske Fokkens
dc.contributor.author Claus Bachert
dc.contributor.author Kristian Aasbjerg
dc.contributor.author Michael Rudenko
dc.contributor.author Arnout Jordens
dc.contributor.author Valérie Hox
dc.contributor.author Joaquim Mullol
dc.contributor.author Paloma Campo
dc.contributor.author Ludger Klimek
dc.contributor.author Evelijn Lourijsen
dc.contributor.author Glenis Scadding
dc.control.author Claus Bachert
dc.date.accessioned 2025-06-19T16:23:39Z
dc.date.available 2025-06-19T16:23:39Z
dc.date.issued 2020-01-03
dc.description.abstract <jats:title>Abstract</jats:title><jats:p>Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that—potentially severe—side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.</jats:p>
dc.description.volume 10
dc.identifier.doi 10.1186/s13601-019-0303-6
dc.identifier.handle 10668/3699
dc.identifier.handle 2445/151863
dc.identifier.handle 11370/f613766b-aab4-4e82-9ce0-674c0fafae65
dc.identifier.handle 2078.1/227171
dc.identifier.handle 2078.1/263157
dc.identifier.handle 10138/313348
dc.identifier.handle 10668/24974
dc.identifier.handle 20.500.12105/17988
dc.identifier.handle 1854/LU-8650078
dc.identifier.issn 2045-7022
dc.identifier.openaire doi_dedup___:faf600bc4193d2045db6743484507c52
dc.identifier.pmc PMC6941282
dc.identifier.pmid 31908763
dc.identifier.uri https://ror.circle-u.eu/handle/123456789/1340906
dc.openaire.affiliation UCLouvain
dc.openaire.collaboration 1
dc.publisher Wiley
dc.rights OPEN
dc.rights.license CC BY
dc.source Clinical and Translational Allergy
dc.subject medical literature
dc.subject evidence based medicine
dc.subject Medical Subject Headings
dc.subject Rhinosinusitis
dc.subject Medical Subject Headings
dc.subject adverse event
dc.subject gastrointestinal symptom
dc.subject otorhinolaryngology
dc.subject eye disease
dc.subject Review
dc.subject nose polyp
dc.subject mental disease
dc.subject systemic therapy
dc.subject Medical Subject Headings
dc.subject DOUBLE-BLIND
dc.subject Adrenal Cortex Hormones
dc.subject cardiovascular disease
dc.subject ORAL STEROIDS
dc.subject lipid metabolism
dc.subject Medicine and Health Sciences
dc.subject SEVERE NASAL POLYPOSIS
dc.subject Cushingoid syndrome
dc.subject Medical Subject Headings
dc.subject Rinitis
dc.subject Rhinitis
dc.subject acute rhinosinusitis
dc.subject alternative medicine
dc.subject drug effect
dc.subject CORTICOSTEROID-THERAPY
dc.subject immunosuppressive treatment
dc.subject nose disease
dc.subject Glucocorticosteroids
dc.subject General medicine, internal medicine and other clinical medicine
dc.subject risk benefit analysis
dc.subject ALLERGIC RHINITIS
dc.subject priority journal
dc.subject protein metabolism
dc.subject SEASONAL
dc.subject diabetes mellitus
dc.subject drug induced disease
dc.subject endocrine disease
dc.subject BONE-MINERAL DENSITY
dc.subject ENDOSCOPIC SINUS SURGERY
dc.subject pediatric patient
dc.subject SEASONAL ALLERGIC RHINITIS
dc.subject hypothalamus hypophysis adrenal system
dc.subject injection site discomfort
dc.subject drug cost
dc.subject desensitization
dc.subject review
dc.subject autoimmune disease
dc.subject fungal sinusitis
dc.subject Pólipos nasales
dc.subject Nasal Polyps
dc.subject WEGENERS-GRANULOMATOSIS
dc.subject drug activity
dc.subject rhinitis
dc.subject short course therapy
dc.subject drug mechanism
dc.subject Humans
dc.subject carbohydrate metabolism
dc.subject human
dc.subject Sinusitis
dc.subject Glucocorticoides
dc.subject Glucocorticoids
dc.subject Corticoesteroides
dc.subject avascular necrosis
dc.subject peptic ulcer
dc.subject Medical Subject Headings
dc.subject drug use
dc.subject long term care
dc.subject allergic rhinitis
dc.subject calcium balance
dc.subject hypophysis disease
dc.subject chronic rhinosinusitis
dc.subject Medical Subject Headings
dc.subject antiinflammatory activity
dc.subject asthma
dc.subject RC581-607
dc.subject osteoporosis
dc.subject infection
dc.subject RHEUMATOID-ARTHRITIS
dc.subject drug efficacy
dc.subject hypothalamus disease
dc.subject upper respiratory tract infection
dc.subject occupational disease
dc.subject glucocorticoid
dc.subject GLUCOCORTICOID-RECEPTOR-ALPHA
dc.subject hyperglycemia
dc.subject Immunologic diseases. Allergy
dc.subject.fos 0302 clinical medicine
dc.subject.fos 03 medical and health sciences
dc.subject.sdg 3. Good health
dc.title Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper
dc.type publication

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