Cas1 and Fen1 Display Equivalent Functions During Archaeal DNA Repair
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Abstract
CRISPR-Cas constitutes an adaptive prokaryotic defence system against invasive nucleic acids like viruses and plasmids. Beyond their role in immunity, CRISPR-Cas systems have been shown to closely interact with components of cellular DNA repair pathways, either by regulating their expression or via direct protein-protein contact and enzymatic activity. The integrase...
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CRISPR-Cas systems , Archaebakterien , Replication protein A , PROTEIN , Plasmid , Gene , Biochemistry , ACTIVATION , Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins , 106005 Bioinformatik , Cas1 , Fen1 , CRISPR-Cas , Haloferax volcanii , info:eu-repo/classification/ddc/610 , info:eu-repo/classification/ddc/570 , 106022 Mikrobiologie , DNS-Reparatur , DNA glycosylase , Life Sciences , QR1-502 , CRISPR , 106022 Microbiology , 106005 Bioinformatics , Cell biology , GENES , archaea , DNA repair , DNA-binding protein , DNA replication , Microbiology , Biochemistry, Genetics and Molecular Biology , Genetics , CRISPR Systems , Molecular Biology , Biology , CRISPR/Cas-Methode , COMPLEX , ACQUISITION , Bacterial Physiology and Genetics , DNA , Archaea , Molecular Mechanisms of DNA Damage Response , Nucleic acid , FOS: Biological sciences , RNA , DNA damage , Transcription factor , SYSTEM